Journal: PLoS ONE
Article Title: The endocannabinoid system in canine Steroid-Responsive Meningitis-Arteritis and Intraspinal Spirocercosis
doi: 10.1371/journal.pone.0187197
Figure Lengend Snippet: Boxes contain values from 1 st to 3 rd quartile, central lines inside the boxes represent median values, and endpoints of vertical lines represent minimum and maximum values, dot (●) represent outliners. Asterisks (*) indicate statistically significant differences (p<0.05). AEA: Anandamide; Total AG: 1-AG (1-arachidonoylglycerol) + 2-AG (2-arachidonoylglycerol); CSF: cerebrospinal fluid; SRMA A: steroid-responsive meningitis-arteritis in acute stage; SRMA Tr: SRMA dogs under treatment; pM: picomolar; nM: nanomolar.
Article Snippet: Additionally, 500 μl of the internal standards d 4 -AEA (Nr. 10011178, Cayman chemical, Michigan, USA) and d 5 -2-AG (Nr. 36162, Cayman chemical, Michigan, USA) were added to each sample, to a final concentration of 1.1 nM and 1.0 nM, respectively.
Techniques: